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Widespread use of incorrect PCR ramp rate negatively impacts multidrug-resistant tuberculosis diagnosis (MTBDRplus)

The scale-up of rapid drug resistance testing for TB is a global priority. MTBDRplus is a WHO-endorsed multidrug-resistant (MDR)-TB PCR assay with suboptimal sensitivities and high indeterminate rates on smear-negative specimens. We hypothesised that widespread use of incorrect thermocycler ramp rat...

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Detalles Bibliográficos
Autores principales:	Derendinger, B., de Vos, M., Nathavitharana, R. R., Dolby, T., Simpson, J. A., van Helden, P. D., Warren, R. M., Theron, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816666/ https://www.ncbi.nlm.nih.gov/pubmed/29453405 http://dx.doi.org/10.1038/s41598-018-21458-y

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