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Scutellarin Increases Cisplatin-Induced Apoptosis and Autophagy to Overcome Cisplatin Resistance in Non-small Cell Lung Cancer via ERK/p53 and c-met/AKT Signaling Pathways
Cisplatin, as the first-line anti-tumor agent, is widely used for treatment of a variety of malignancies including non-small cell lung cancer (NSCLC). However, the acquired resistance has been a major obstacle for the clinical application. Scutellarin is a active flavone extracted from Erigeron brev...
Autores principales: | Sun, Chao-Yue, Zhu, Ying, Li, Xiao-Feng, Wang, Xie-Qi, Tang, Li-Peng, Su, Zu-Qing, Li, Cai-Yun, Zheng, Guang-Juan, Feng, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816782/ https://www.ncbi.nlm.nih.gov/pubmed/29487530 http://dx.doi.org/10.3389/fphar.2018.00092 |
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