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Positive Charges on the Surface of Thaumatin Are Crucial for the Multi-Point Interaction with the Sweet Receptor

Thaumatin, an intensely sweet-tasting protein, elicits sweet taste with a threshold of only 50 nM. Previous studies from our laboratory suggested that the complex model between the T1R2-T1R3 sweet receptor and thaumatin depends critically on the complementarity of electrostatic potentials. In order...

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Detalles Bibliográficos
Autores principales: Masuda, Tetsuya, Kigo, Satomi, Mitsumoto, Mayuko, Ohta, Keisuke, Suzuki, Mamoru, Mikami, Bunzo, Kitabatake, Naofumi, Tani, Fumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816810/
https://www.ncbi.nlm.nih.gov/pubmed/29487853
http://dx.doi.org/10.3389/fmolb.2018.00010