Research Advances in the Correlation between Peroxisome Proliferator-Activated Receptor-γ and Digestive Cancers

Peroxisome proliferator-activated receptor-γ (PPARγ) is a class of ligand-activated nuclear transcription factors, which is a member of type II nuclear receptor superfamily. Previous studies demonstrate that PPARγ is expressed in a variety of tumor tissues and is closely associated with the prolifer...

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Detalles Bibliográficos
Autores principales: Xu, Shuqi, Xu, Xuanfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816837/
https://www.ncbi.nlm.nih.gov/pubmed/29483923
http://dx.doi.org/10.1155/2018/5289859
Descripción
Sumario:Peroxisome proliferator-activated receptor-γ (PPARγ) is a class of ligand-activated nuclear transcription factors, which is a member of type II nuclear receptor superfamily. Previous studies demonstrate that PPARγ is expressed in a variety of tumor tissues and is closely associated with the proliferation and prognosis of digestive system tumors by its roles in mediation of cell differentiation, induction of cell apoptosis, and inhibition of cell proliferation.

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