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Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls

Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We de...

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Autores principales: Serrano Rodriguez, Pablo, Barritt IV, Alfred Sidney, Gerber, David Allen, Desai, Chirag Sureshchandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816892/
https://www.ncbi.nlm.nih.gov/pubmed/29487756
http://dx.doi.org/10.1155/2018/4863187
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author Serrano Rodriguez, Pablo
Barritt IV, Alfred Sidney
Gerber, David Allen
Desai, Chirag Sureshchandra
author_facet Serrano Rodriguez, Pablo
Barritt IV, Alfred Sidney
Gerber, David Allen
Desai, Chirag Sureshchandra
author_sort Serrano Rodriguez, Pablo
collection PubMed
description Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We describe two cases who had exceedingly large livers, weighing 14 and 19 kg. To the best of our knowledge and search, these are some of the heaviest explanted livers, and one of the patients incidentally received a liver from a donor with ADPKD. The aim of this report is to discuss the challenges and pitfalls of evaluating and listing, technical aspect of the transplant, possibility of transplanting a liver from a donor with a genetic cystic disease to a cystic disease recipient, and the related literature with some highlights on the facts from UNOS/OPTN data.
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spelling pubmed-58168922018-02-27 Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls Serrano Rodriguez, Pablo Barritt IV, Alfred Sidney Gerber, David Allen Desai, Chirag Sureshchandra Case Rep Transplant Case Report Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We describe two cases who had exceedingly large livers, weighing 14 and 19 kg. To the best of our knowledge and search, these are some of the heaviest explanted livers, and one of the patients incidentally received a liver from a donor with ADPKD. The aim of this report is to discuss the challenges and pitfalls of evaluating and listing, technical aspect of the transplant, possibility of transplanting a liver from a donor with a genetic cystic disease to a cystic disease recipient, and the related literature with some highlights on the facts from UNOS/OPTN data. Hindawi 2018-02-01 /pmc/articles/PMC5816892/ /pubmed/29487756 http://dx.doi.org/10.1155/2018/4863187 Text en Copyright © 2018 Pablo Serrano Rodriguez et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Serrano Rodriguez, Pablo
Barritt IV, Alfred Sidney
Gerber, David Allen
Desai, Chirag Sureshchandra
Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
title Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
title_full Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
title_fullStr Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
title_full_unstemmed Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
title_short Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
title_sort liver transplant for unusually large polycystic liver disease: challenges and pitfalls
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816892/
https://www.ncbi.nlm.nih.gov/pubmed/29487756
http://dx.doi.org/10.1155/2018/4863187
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