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Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls
Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We de...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816892/ https://www.ncbi.nlm.nih.gov/pubmed/29487756 http://dx.doi.org/10.1155/2018/4863187 |
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author | Serrano Rodriguez, Pablo Barritt IV, Alfred Sidney Gerber, David Allen Desai, Chirag Sureshchandra |
author_facet | Serrano Rodriguez, Pablo Barritt IV, Alfred Sidney Gerber, David Allen Desai, Chirag Sureshchandra |
author_sort | Serrano Rodriguez, Pablo |
collection | PubMed |
description | Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We describe two cases who had exceedingly large livers, weighing 14 and 19 kg. To the best of our knowledge and search, these are some of the heaviest explanted livers, and one of the patients incidentally received a liver from a donor with ADPKD. The aim of this report is to discuss the challenges and pitfalls of evaluating and listing, technical aspect of the transplant, possibility of transplanting a liver from a donor with a genetic cystic disease to a cystic disease recipient, and the related literature with some highlights on the facts from UNOS/OPTN data. |
format | Online Article Text |
id | pubmed-5816892 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58168922018-02-27 Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls Serrano Rodriguez, Pablo Barritt IV, Alfred Sidney Gerber, David Allen Desai, Chirag Sureshchandra Case Rep Transplant Case Report Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We describe two cases who had exceedingly large livers, weighing 14 and 19 kg. To the best of our knowledge and search, these are some of the heaviest explanted livers, and one of the patients incidentally received a liver from a donor with ADPKD. The aim of this report is to discuss the challenges and pitfalls of evaluating and listing, technical aspect of the transplant, possibility of transplanting a liver from a donor with a genetic cystic disease to a cystic disease recipient, and the related literature with some highlights on the facts from UNOS/OPTN data. Hindawi 2018-02-01 /pmc/articles/PMC5816892/ /pubmed/29487756 http://dx.doi.org/10.1155/2018/4863187 Text en Copyright © 2018 Pablo Serrano Rodriguez et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Serrano Rodriguez, Pablo Barritt IV, Alfred Sidney Gerber, David Allen Desai, Chirag Sureshchandra Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls |
title | Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls |
title_full | Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls |
title_fullStr | Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls |
title_full_unstemmed | Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls |
title_short | Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls |
title_sort | liver transplant for unusually large polycystic liver disease: challenges and pitfalls |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816892/ https://www.ncbi.nlm.nih.gov/pubmed/29487756 http://dx.doi.org/10.1155/2018/4863187 |
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