Sub-cellular Electrical Heterogeneity Revealed by Loose Patch Recording Reflects Differential Localization of Sarcolemmal Ion Channels in Intact Rat Hearts

The cardiac action potential (AP) is commonly recoded as an integral signal from isolated myocytes or ensembles of myocytes (with intracellular microelectrodes and extracellular macroelectrodes, respectively). These signals, however, do not provide a direct measure of activity of ion channels and tr...

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Detalles Bibliográficos
Autores principales: Kubasov, Igor V., Stepanov, Andrei, Bobkov, Danila, Radwanski, Przemysław B., Terpilowski, Maxim A., Dobretsov, Maxim, Gyorke, Sandor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816904/
https://www.ncbi.nlm.nih.gov/pubmed/29487533
http://dx.doi.org/10.3389/fphys.2018.00061

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