Beta-Defensin 2 and 3 Promote Bacterial Clearance of Pseudomonas aeruginosa by Inhibiting Macrophage Autophagy through Downregulation of Early Growth Response Gene-1 and c-FOS

Beta-defensins 2 and 3 (BD2 and BD3) are inducible peptides present at the sites of infection, and they are well characterized for their antimicrobial activities and immune-regulatory functions. However, no study has thoroughly investigated their immunomodulatory effects on macrophage-mediated immun...

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Detalles Bibliográficos
Autores principales: Wu, Yongjian, Li, Dandan, Wang, Yi, Liu, Xi, Zhang, Yuanqing, Qu, Wenting, Chen, Kang, Francisco, Ngiambudulu M., Feng, Lianqiang, Huang, Xi, Wu, Minhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816924/
https://www.ncbi.nlm.nih.gov/pubmed/29487594
http://dx.doi.org/10.3389/fimmu.2018.00211

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