Cargando…

Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus

Zika virus (ZIKV) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the Americas. Aedes mosquitoes are the primary vectors for ZIKV, but little is known about the diversity of mosquitoes that can transmit ZIKV in North America. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Dodson, Brittany L., Pujhari, Sujit, Rasgon, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816964/
https://www.ncbi.nlm.nih.gov/pubmed/29472998
http://dx.doi.org/10.7717/peerj.4324
_version_ 1783300789585838080
author Dodson, Brittany L.
Pujhari, Sujit
Rasgon, Jason L.
author_facet Dodson, Brittany L.
Pujhari, Sujit
Rasgon, Jason L.
author_sort Dodson, Brittany L.
collection PubMed
description Zika virus (ZIKV) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the Americas. Aedes mosquitoes are the primary vectors for ZIKV, but little is known about the diversity of mosquitoes that can transmit ZIKV in North America. We chose three abundant North American mosquito species (Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis) and one known vector species (Aedes aegypti), fed them blood meals supplemented with a recent outbreak ZIKV strain, and tested bodies, legs, and saliva for infectious ZIKV. ZIKV was able to infect, disseminate, and be transmitted by Aedes aegypti. However, Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis were unable to be infected. We conclude that these species are unlikely to be involved in ZIKV transmission in North America. However, we should continue to examine the ability for other mosquito species to potentially act as ZIKV vectors in North America.
format Online
Article
Text
id pubmed-5816964
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher PeerJ Inc.
record_format MEDLINE/PubMed
spelling pubmed-58169642018-02-22 Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus Dodson, Brittany L. Pujhari, Sujit Rasgon, Jason L. PeerJ Entomology Zika virus (ZIKV) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the Americas. Aedes mosquitoes are the primary vectors for ZIKV, but little is known about the diversity of mosquitoes that can transmit ZIKV in North America. We chose three abundant North American mosquito species (Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis) and one known vector species (Aedes aegypti), fed them blood meals supplemented with a recent outbreak ZIKV strain, and tested bodies, legs, and saliva for infectious ZIKV. ZIKV was able to infect, disseminate, and be transmitted by Aedes aegypti. However, Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis were unable to be infected. We conclude that these species are unlikely to be involved in ZIKV transmission in North America. However, we should continue to examine the ability for other mosquito species to potentially act as ZIKV vectors in North America. PeerJ Inc. 2018-02-15 /pmc/articles/PMC5816964/ /pubmed/29472998 http://dx.doi.org/10.7717/peerj.4324 Text en ©2018 Dodson et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Entomology
Dodson, Brittany L.
Pujhari, Sujit
Rasgon, Jason L.
Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus
title Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus
title_full Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus
title_fullStr Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus
title_full_unstemmed Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus
title_short Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus
title_sort vector competence of selected north american anopheles and culex mosquitoes for zika virus
topic Entomology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816964/
https://www.ncbi.nlm.nih.gov/pubmed/29472998
http://dx.doi.org/10.7717/peerj.4324
work_keys_str_mv AT dodsonbrittanyl vectorcompetenceofselectednorthamericananophelesandculexmosquitoesforzikavirus
AT pujharisujit vectorcompetenceofselectednorthamericananophelesandculexmosquitoesforzikavirus
AT rasgonjasonl vectorcompetenceofselectednorthamericananophelesandculexmosquitoesforzikavirus