Direct Reprogramming of Spiral Ganglion Non-neuronal Cells into Neurons: Toward Ameliorating Sensorineural Hearing Loss by Gene Therapy

Primary auditory neurons (PANs) play a critical role in hearing by transmitting sound information from the inner ear to the brain. Their progressive degeneration is associated with excessive noise, disease and aging. The loss of PANs leads to permanent hearing impairment since they are incapable of...

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Detalles Bibliográficos
Autores principales: Noda, Teppei, Meas, Steven J., Nogami, Jumpei, Amemiya, Yutaka, Uchi, Ryutaro, Ohkawa, Yasuyuki, Nishimura, Koji, Dabdoub, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817057/
https://www.ncbi.nlm.nih.gov/pubmed/29492404
http://dx.doi.org/10.3389/fcell.2018.00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817057/
https://www.ncbi.nlm.nih.gov/pubmed/29492404
http://dx.doi.org/10.3389/fcell.2018.00016

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