Cargando…

Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway

Osteopontin (OPN), a chemokine-like protein, plays a crucial role in the proliferation and metastasis of various cancers. However, how tumor stroma modulates the expression of neoplastic OPN and the multifaceted roles of OPN in head and neck cancer (HNC) are unclear. In this study, we tried to inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Xing, Yan, Ming, Wang, Xu, Xu, Qin, Wang, Xiaoning, Zhu, Xueqin, Shi, Jianbo, Li, Zhihui, Zhang, Jianjun, Chen, Wantao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817102/ https://www.ncbi.nlm.nih.gov/pubmed/29463991 http://dx.doi.org/10.7150/thno.22182

Ejemplares similares

Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway: Erratum
por: Qin, Xing, et al.
Publicado: (2022)

Exosomal miR-196a derived from cancer-associated fibroblasts confers cisplatin resistance in head and neck cancer through targeting CDKN1B and ING5
por: Qin, Xing, et al.
Publicado: (2019)

Loss of exosomal miR-3188 in cancer-associated fibroblasts contributes to HNC progression
por: Wang, Xiaoning, et al.
Publicado: (2019)

Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7
por: Yu, Binbin, et al.
Publicado: (2018)

CD147 promotes progression of head and neck squamous cell carcinoma via NF‐kappa B signaling
por: Yu, Binbin, et al.
Publicado: (2018)

TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis
por: Qin, Xing, et al.
Publicado: (2016)

Cancer stem-like cell related protein CD166 degrades through E3 ubiquitin ligase CHIP in head and neck cancer
por: Xiao, Meng, et al.
Publicado: (2017)

TGM3, a candidate tumor suppressor gene, contributes to human head and neck cancer
por: Wu, Xiangbing, et al.
Publicado: (2013)

Osteopontin Levels in Patients with Squamous Metastatic Head and Neck Cancer
por: Maleš, Josip, et al.
Publicado: (2021)

LncRNA LINC00460 promotes EMT in head and neck squamous cell carcinoma by facilitating peroxiredoxin-1 into the nucleus
por: Jiang, Yingying, et al.
Publicado: (2019)

Oral cancer cell-derived exosomes modulate natural killer cell activity by regulating the receptors on these cells
por: Zhu, Xueqin, et al.
Publicado: (2020)

The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
por: He, Di, et al.
Publicado: (2009)

A new gamboge derivative Compound 2 inhibits cancer stem-like cells via suppressing EGFR tyrosine phosphorylation in head and neck squamous cell carcinoma
por: Deng, Rongxin, et al.
Publicado: (2013)

Caveolin‐1 promotes cancer progression via inhibiting ferroptosis in head and neck squamous cell carcinoma
por: Lu, Tingwei, et al.
Publicado: (2021)

Influence of hypoxia and irradiation on osteopontin expression in head and neck cancer and glioblastoma cell lines
por: Wohlleben, Gisela, et al.
Publicado: (2015)

Targeting epigenetic modulation of cholesterol synthesis as a therapeutic strategy for head and neck squamous cell carcinoma
por: Xu, Xing, et al.
Publicado: (2021)

NF-kappaB-dependent MicroRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction
por: Ma, Jun, et al.
Publicado: (2014)

Plasma osteopontin levels in patients with head and neck cancer and cervix cancer are critically dependent on the choice of ELISA system
por: Vordermark, Dirk, et al.
Publicado: (2006)

The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis
por: Xu, Kun, et al.
Publicado: (2016)

Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma
por: Zhang, Tingting, et al.
Publicado: (2021)

Unraveling Regulatory Programs for NF-kappaB, p53 and MicroRNAs in Head and Neck Squamous Cell Carcinoma
por: Yan, Bin, et al.
Publicado: (2013)

Heterogeneity of cancer-associated fibroblasts in head and neck squamous cell carcinoma
por: Mou, Tingchen, et al.
Publicado: (2023)

Perioperative changes in osteopontin and TGFβ1 plasma levels and their prognostic impact for radiotherapy in head and neck cancer
por: Polat, Bülent, et al.
Publicado: (2017)

Cancer-associated fibroblasts promote cancer cell growth through a miR-7-RASSF2-PAR-4 axis in the tumor microenvironment
por: Shen, Zongze, et al.
Publicado: (2016)

IL-1/IL-1R Signaling in Head and Neck Cancer
por: Niklander, Sven E., et al.
Publicado: (2021)

Immunohistochemical analysis of cancer-associated fibroblasts and podoplanin in head and neck cancer
por: Ramos-Vega, Víctor, et al.
Publicado: (2020)

A Novel Tumor Suppressor SPINK5 Serves as an Independent Prognostic Predictor for Patients with Head and Neck Squamous Cell Carcinoma
por: Lv, Zhongjing, et al.
Publicado: (2020)

Isolation and characterization of head and neck cancer-derived peritumoral and cancer-associated fibroblasts
por: Zhou, Jiefu, et al.
Publicado: (2022)

Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells
por: Li, Juan, et al.
Publicado: (2012)

Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3–1 cells: Recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene
por: Finotti, Alessia, et al.
Publicado: (2012)

NF-kappaB Regulates Redox Status in Breast Cancer Subtypes
por: Pires, Bruno R. B., et al.
Publicado: (2018)

NF-kappaB in Lung Tumorigenesis
por: Cai, Zhenjian, et al.
Publicado: (2011)

Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior
por: Chien, Chih-Yen, et al.
Publicado: (2014)

Age-Related Cancer-Associated Microbiota Potentially Promotes Oral Squamous Cell Cancer Tumorigenesis by Distinct Mechanisms
por: Zhang, Zhen, et al.
Publicado: (2022)

Dysregulated miR-645 affects the proliferation and invasion of head and neck cancer cell
por: Sun, Qiang, et al.
Publicado: (2015)

An Update on the Multifaceted Role of NF-kappaB in Endometriosis
por: Liu, Yuanmeng, et al.
Publicado: (2022)

IL-6 in the Ecosystem of Head and Neck Cancer: Possible Therapeutic Perspectives
por: Španko, Michal, et al.
Publicado: (2021)

Overexpression of EMMPRIN Isoform 2 Is Associated with Head and Neck Cancer Metastasis
por: Huang, Zhiquan, et al.
Publicado: (2014)

Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB
por: Solomon, Leigh A, et al.
Publicado: (2008)

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells
por: Pires, Bruno R. B., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rsd818im8iclesm2otqdkeg0i3