Chronic intermittent hypobaric hypoxia attenuates monocrotaline-induced pulmonary arterial hypertension via modulating inflammation and suppressing NF-κB/p38 pathway

OBJECTIVE(S): Inflammation is involved in various forms of pulmonary arterial hypertension (PAH). Although the pathophysiology of PAH remains uncertain, NF-κB and p38 mitogen-activated protein kinase (p38 MAPK) has been reported to be associated with many inflammatory mediators of PAH. This study ai...

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Detalles Bibliográficos
Autores principales: Gao, Lei, Liu, Jun, Hao, Yongmei, Zhao, Zengren, Tan, Huilian, Zhang, Jie, Meng, Ning, Zheng, Qinghou, Wang, Zhen, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817167/
https://www.ncbi.nlm.nih.gov/pubmed/29511490
http://dx.doi.org/10.22038/ijbms.2018.25399.6280

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