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Design of a humanized anti vascular endothelial growth factor nanobody and evaluation of its in vitro function
OBJECTIVE(S): Nanobodies, the single domain antigen binding fragments of heavy chain-only antibodies occurring naturally in camelid sera, are the smallest intact antigen binding entities. Their minimal size assists in reaching otherwise largely inaccessible regions of antigens. However, their cameli...
Autores principales: | Kazemi-Lomedasht, Fatemeh, Muyldermans, Serge, Habibi-Anbouhi, Mahdi, Behdani, Mahdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817169/ https://www.ncbi.nlm.nih.gov/pubmed/29511492 http://dx.doi.org/10.22038/ijbms.2018.24898.6183 |
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