Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides

The use of carbonyl‐stabilized ammonium‐ and sulfonium ylides allows for the synthesis of highly‐functionalized trifluoroacetyl‐substituted cyclopropanes. It turned out that the diastereoselectivities strongly depend on the nature of the chosen ylide and the employed base. The products could be obta...

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Autores principales: Winter, Michael, Gaunersdorfer, Christina, Roiser, Lukas, Zielke, Katharina, Monkowius, Uwe, Waser, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817241/
https://www.ncbi.nlm.nih.gov/pubmed/29491744
http://dx.doi.org/10.1002/ejoc.201701699
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author Winter, Michael
Gaunersdorfer, Christina
Roiser, Lukas
Zielke, Katharina
Monkowius, Uwe
Waser, Mario
author_facet Winter, Michael
Gaunersdorfer, Christina
Roiser, Lukas
Zielke, Katharina
Monkowius, Uwe
Waser, Mario
author_sort Winter, Michael
collection PubMed
description The use of carbonyl‐stabilized ammonium‐ and sulfonium ylides allows for the synthesis of highly‐functionalized trifluoroacetyl‐substituted cyclopropanes. It turned out that the diastereoselectivities strongly depend on the nature of the chosen ylide and the employed base. The products could be obtained in good yields under operationally simple conditions.
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spelling pubmed-58172412018-02-26 Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides Winter, Michael Gaunersdorfer, Christina Roiser, Lukas Zielke, Katharina Monkowius, Uwe Waser, Mario European J Org Chem Communications The use of carbonyl‐stabilized ammonium‐ and sulfonium ylides allows for the synthesis of highly‐functionalized trifluoroacetyl‐substituted cyclopropanes. It turned out that the diastereoselectivities strongly depend on the nature of the chosen ylide and the employed base. The products could be obtained in good yields under operationally simple conditions. John Wiley and Sons Inc. 2018-01-22 2018-01-23 /pmc/articles/PMC5817241/ /pubmed/29491744 http://dx.doi.org/10.1002/ejoc.201701699 Text en © 2018 The Authors. Published by Wiley‐VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Winter, Michael
Gaunersdorfer, Christina
Roiser, Lukas
Zielke, Katharina
Monkowius, Uwe
Waser, Mario
Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides
title Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides
title_full Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides
title_fullStr Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides
title_full_unstemmed Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides
title_short Synthesis of Trifluoroacetyl‐Substituted Cyclopropanes Using Onium Ylides
title_sort synthesis of trifluoroacetyl‐substituted cyclopropanes using onium ylides
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817241/
https://www.ncbi.nlm.nih.gov/pubmed/29491744
http://dx.doi.org/10.1002/ejoc.201701699
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