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A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders

Protein ubiquitination is a posttranslational modification that plays an integral part in mediating diverse cellular functions. The process of protein ubiquitination requires an enzymatic cascade that consists of a ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2) and an E3 ubiquit...

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Detalles Bibliográficos
Autores principales: George, Arlene J., Hoffiz, Yarely C., Charles, Antoinette J., Zhu, Ying, Mabb, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817383/
https://www.ncbi.nlm.nih.gov/pubmed/29491882
http://dx.doi.org/10.3389/fgene.2018.00029

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