Epigenomics alternations and dynamic transcriptional changes in responses to 5-fluorouracil stimulation reveal mechanisms of acquired drug resistance of colorectal cancer cells

A drug-induced resistant cancer cell is different from its parent cell in transcriptional response to drug treatment. The distinct transcriptional response pattern of a drug-induced resistant cancer cell to drug treatment might be introduced by acquired DNA methylation aberration in the cell exposin...

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Detalles Bibliográficos
Autores principales: Shen, Y, Tong, M, Liang, Q, Guo, Y, Sun, H Q, Zheng, W, Ao, L, Guo, Z, She, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817391/
https://www.ncbi.nlm.nih.gov/pubmed/28045128
http://dx.doi.org/10.1038/tpj.2016.91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817391/
https://www.ncbi.nlm.nih.gov/pubmed/28045128
http://dx.doi.org/10.1038/tpj.2016.91

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