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Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles

BACKGROUND: We report the development of an efficient antibody delivery system for the incorporation of trastuzumab (TZ) into poly(lactic-co-glycolic) acid nanoparticles (PLGA NPs). The aim of the work was to overcome the current limitations in the clinical use of therapeutic antibodies, including i...

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Detalles Bibliográficos
Autores principales:	Colzani, Barbara, Pandolfi, Laura, Hoti, Ada, Iovene, Pietro Alessandro, Natalello, Antonino, Avvakumova, Svetlana, Colombo, Miriam, Prosperi, Davide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817418/ https://www.ncbi.nlm.nih.gov/pubmed/29491709 http://dx.doi.org/10.2147/IJN.S152742

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