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DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data
BACKGROUND: DNA methylation is an epigenetic modification that is studied at a single-base resolution with bisulfite treatment followed by high-throughput sequencing. After alignment of the sequence reads to a reference genome, methylation counts are analyzed to determine genomic regions that are di...
Autores principales: | Gaspar, John M., Hart, Ronald P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817627/ https://www.ncbi.nlm.nih.gov/pubmed/29187143 http://dx.doi.org/10.1186/s12859-017-1909-0 |
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