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PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the development and progression of cancers. Receptor tyrosine kina...

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Detalles Bibliográficos
Autores principales:	Haddadi, Nahal, Lin, Yiguang, Travis, Glena, Simpson, Ann M., McGowan, Eileen M., Nassif, Najah T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817727/ https://www.ncbi.nlm.nih.gov/pubmed/29455665 http://dx.doi.org/10.1186/s12943-018-0803-3

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