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Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway

The insulin-like growth factor-1 receptor (IGF1R) has been identified as a potent anti-apoptotic, pro-survival tyrosine kinase-containing receptor. Overexpression of the IGF1R gene constitutes a typical feature of most human cancers. Consistent with these biological roles, cells expressing high leve...

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Detalles Bibliográficos
Autores principales:	Werner, Haim, Meisel-Sharon, Shilhav, Bruchim, Ilan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817802/ https://www.ncbi.nlm.nih.gov/pubmed/29455671 http://dx.doi.org/10.1186/s12943-018-0807-z

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