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Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: Comparisons between pharmacological inhibition and selective shRNA knockdown approaches

As a target, the JNK pathway has been implicated in roles including cell death, proliferation, and inflammation in variety of contexts which span cardiovascular disease, neurodegenerative pathologies, and cancer. JNK1 and JNK2 have recently been demonstrated to function independently, highlighting a...

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Detalles Bibliográficos
Autores principales: Wood, Rachel A., Barbour, Mark J., Gould, Gwyn W., Cunningham, Margaret R., Plevin, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817830/
https://www.ncbi.nlm.nih.gov/pubmed/29417765
http://dx.doi.org/10.1002/prp2.376