Cargando…

Effect of desipramine on patients with breathing disorders in RETT syndrome

OBJECTIVE: Rett Syndrome (RTT) is a severe neurodevelopmental condition with breathing disorders, affecting around one in 10,000 female births. Desipramine, a noradrenaline reuptake inhibitor, reduced the number of apneas in Mecp2‐deficient mice, a model of RTT. We planned a phase 2 trial to test it...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mancini, Josette, Dubus, Jean‐Christophe, Jouve, Elisabeth, Roux, Jean‐Christophe, Franco, Patricia, Lagrue, Emmanuelle, Castelnau, Pierre, Cances, Claude, Chaix, Yves, Rougeot‐Jung, Christelle, Cornu, Catherine, Desportes, Vincent, Vallée, Louis, Bahi‐Buisson, Nadia, Truillet, Romain, Attolini, Laurence, Villard, Laurent, Blin, Olivier, Micallef, Joëlle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817841/ https://www.ncbi.nlm.nih.gov/pubmed/29468173 http://dx.doi.org/10.1002/acn3.468

Ejemplares similares

Rett syndrome: think outside the (skull) box
por: Borloz, Emilie, et al.
Publicado: (2021)

Rett syndrome from bench to bedside: recent advances
por: Ehinger, Yann, et al.
Publicado: (2018)

What Do We Know About Medical Cannabis in Neurological Disorders and What Are the Next Steps?
por: Lacroix, Clémence, et al.
Publicado: (2022)

Cell cloning-based transcriptome analysis in Rett patients: relevance to the pathogenesis of Rett syndrome of new human MeCP2 target genes
por: Nectoux, J, et al.
Publicado: (2010)

Anti-inflammatory properties of desipramine and fluoxetine
por: Roumestan, Caroline, et al.
Publicado: (2007)

Analysis of the Phenotypes in the Rett Networked Database
por: Frullanti, Elisa, et al.
Publicado: (2019)

State‐of‐the‐art therapies for Rett syndrome
por: Panayotis, Nicolas, et al.
Publicado: (2022)

Analysis of Astroglial Secretomic Profile in the Mecp2-Deficient Male Mouse Model of Rett Syndrome
por: Ehinger, Yann, et al.
Publicado: (2021)

Desipramine hydrochloride: a non-merohedrally twinned structure
por: Jasinski, Jerry P., et al.
Publicado: (2010)

Lower incidence of fracture after IV bisphosphonates in girls with Rett syndrome and severe bone fragility
por: Lambert, Anne-Sophie, et al.
Publicado: (2017)

Tricyclic Antidepressants Amitriptyline and Desipramine Induced Neurotoxicity Associated with Parkinson’s Disease
por: Lee, Min-yeong, et al.
Publicado: (2015)

Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids
por: Spulber, Stefan, et al.
Publicado: (2019)

Cytoprotection of rat hepatocytes by desipramine in a model of simulated ischemia/reperfusion
por: Shin, Jun-Kyu, et al.
Publicado: (2021)

Desipramine enhances the stability of atherosclerotic plaque in rabbits monitored with molecular imaging
por: Zhao, Min, et al.
Publicado: (2023)

Orphandev, French Clinical Trials Network dedicated to Orphan drugs and therapeutics development for rare diseases
por: Adjibi, Yolande, et al.
Publicado: (2010)

Sporadic and Familial Variants in NF1: An Explanation of the Wide Variability in Neurocognitive Phenotype?
por: Biotteau, Maëlle, et al.
Publicado: (2020)

Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model
por: Aga-Mizrachi, S, et al.
Publicado: (2014)

Desipramine Pretreatment Improves Sympathetic Remodeling and Ventricular Fibrillation Threshold after Myocardial Ischemia
por: Wu, Xiaolin, et al.
Publicado: (2012)

New ligand-binding sites identified in the crystal structures of β-lactoglobulin complexes with desipramine
por: Loch, Joanna I., et al.
Publicado: (2022)

Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport
por: Lagrue, Emmanuelle, et al.
Publicado: (2010)

Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration
por: Deupree, Jean D, et al.
Publicado: (2008)

Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates
por: Guo, M, et al.
Publicado: (2014)

Metabolic Fingerprints of Altered Brain Growth, Osmoregulation and Neurotransmission in a Rett Syndrome Model
por: Viola, Angèle, et al.
Publicado: (2007)

Desipramine Inhibits Histamine H1 Receptor-Induced Ca(2+) Signaling in Rat Hypothalamic Cells
por: Kang, Ji-Ah, et al.
Publicado: (2012)

Revisiting the antidepressant-like effects of desipramine in male and female adult rats: sex disparities in neurochemical correlates
por: Ledesma-Corvi, Sandra, et al.
Publicado: (2022)

Calcium-Dependent Interplay of Lithium and Tricyclic Antidepressants, Amitriptyline and Desipramine, on N-methyl-D-aspartate Receptors
por: Boikov, Sergei I., et al.
Publicado: (2022)

Rett syndrome
por: Sitholey, Prabhat, et al.
Publicado: (2005)

Desipramine treatment has minimal effects on the brain accumulation of glucocorticoids in P-gp-deficient and wild-type mice
por: Mason, Brittany L., et al.
Publicado: (2011)

Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram
por: Choi, Sun Hye, et al.
Publicado: (2013)

Development and Qualification of Physiologically Based Pharmacokinetic Models for Drugs With Atypical Distribution Behavior: A Desipramine Case Study
por: Samant, TS, et al.
Publicado: (2017)

Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines
por: Kubera, Marta, et al.
Publicado: (2023)

Adaptability and reproducibility of a memory disruption rTMS protocol in the PharmaCog IMI European project
por: Martin-Trias, Pablo, et al.
Publicado: (2018)

Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice
por: Socała, Katarzyna, et al.
Publicado: (2012)

Desipramine Protects Neuronal Cell Death and Induces Heme Oxygenase-1 Expression in Mes23.5 Dopaminergic Neurons
por: Lin, Hsiao-Yun, et al.
Publicado: (2012)

Nebulization and COVID-19: Is the risk of spread actual?
por: Thibon, Christophe, et al.
Publicado: (2022)

When Christmas decoration goes hand in hand with bronchial aspiration …
por: Carsin, Ania, et al.
Publicado: (2017)

Sensory Integration and Functional Reaching in Children With Rett Syndrome/Rett-Related Disorders
por: Drobnyk, Wendy, et al.
Publicado: (2019)

Sleep Disorders in Rett Syndrome and Rett-Related Disorders: A Narrative Review
por: Tascini, Giorgia, et al.
Publicado: (2022)

PS124. Effects of desipramine, venlafaxine and bupropion on depression and anxiety in the forced swimming test and elevated plus maze test in mice
por: Tanyeri, Mehmet Hanifi, et al.
Publicado: (2016)

Author Correction: BDNF Val66Met gene polymorphism modulates brain activity following rTMS-induced memory impairment
por: Abellaneda‑Pérez, Kilian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a15fvc9ftosmulcfbbilr347bm