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The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant diseases worldwide. It is refractory to conventional treatments, and consequently has a documented 5-year survival rate as low as 7%. Increasing evidence indicates that activated pancreatic stellate cells (PSCs), one of the...

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Detalles Bibliográficos
Autores principales: Fu, Yaojie, Liu, Shanshan, Zeng, Shan, Shen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817854/
https://www.ncbi.nlm.nih.gov/pubmed/29458370
http://dx.doi.org/10.1186/s12943-018-0815-z