Kinase-targeted cancer therapies: progress, challenges and future directions

The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with human cancer initiation and progression. The recent development of small-molecule kinase inhibitors for the treatment of diver...

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Detalles Bibliográficos
Autores principales: Bhullar, Khushwant S., Lagarón, Naiara Orrego, McGowan, Eileen M., Parmar, Indu, Jha, Amitabh, Hubbard, Basil P., Rupasinghe, H. P. Vasantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817855/
https://www.ncbi.nlm.nih.gov/pubmed/29455673
http://dx.doi.org/10.1186/s12943-018-0804-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817855/
https://www.ncbi.nlm.nih.gov/pubmed/29455673
http://dx.doi.org/10.1186/s12943-018-0804-2

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