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Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Breast cancer is a multifactorial disease and driven by aberrant regulation of cell signaling pathways due to the acquisition of genetic and epigenetic changes. An array of growth factors and their receptors is involved in cancer development and metastasis. Receptor Tyrosine Kinases (RTKs) constitut...

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Detalles Bibliográficos
Autores principales:	Butti, Ramesh, Das, Sumit, Gunasekaran, Vinoth Prasanna, Yadav, Amit Singh, Kumar, Dhiraj, Kundu, Gopal C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817867/ https://www.ncbi.nlm.nih.gov/pubmed/29455658 http://dx.doi.org/10.1186/s12943-018-0797-x

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