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Evolvability of Amyloidogenic Proteins in Human Brain

 Currently, the physiological roles of amyloidogenic proteins (APs) in human brain, such as amyloid-β and α-synuclein, are elusive. Given that many APs arose by gene duplication and have been resistant against the pressures of natural selection, APs may be associated with some functions that are adv...

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Detalles Bibliográficos
Autores principales: Hashimoto, Makoto, Ho, Gilbert, Sugama, Shuei, Takamatsu, Yoshiki, Shimizu, Yuka, Takenouchi, Takato, Waragai, Masaaki, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817905/
https://www.ncbi.nlm.nih.gov/pubmed/29439348
http://dx.doi.org/10.3233/JAD-170894