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PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP

Our previous studies of PAWS1 (protein associated with SMAD1; also known as FAM83G) have suggested that this molecule has roles beyond BMP signalling. To investigate these roles, we have used CRISPR/Cas9 to generate PAWS1-knockout U2OS osteosarcoma cells. Here, we show that PAWS1 plays a role in the...

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Detalles Bibliográficos
Autores principales:	Cummins, Timothy D., Wu, Kevin Z. L., Bozatzi, Polyxeni, Dingwell, Kevin S., Macartney, Thomas J., Wood, Nicola T., Varghese, Joby, Gourlay, Robert, Campbell, David G., Prescott, Alan, Griffis, Eric, Smith, James C., Sapkota, Gopal P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818054/ https://www.ncbi.nlm.nih.gov/pubmed/29175910 http://dx.doi.org/10.1242/jcs.202390

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