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Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney
The final nephron number in an adult kidney is regulated by nephron progenitor cell availability and collecting duct branching in the fetal period. Fetal environmental perturbations that cause reductions in cell numbers in these two compartments result in low nephron endowment. Previous work has sho...
Autores principales: | Muthukrishnan, Sree Deepthi, Ryzhov, Sergey, Karolak, Michele, Oxburgh, Leif |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818074/ https://www.ncbi.nlm.nih.gov/pubmed/29196442 http://dx.doi.org/10.1242/dmm.030544 |
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