Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia

Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. A...

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Autores principales: Venter, Fredrick, Heidari, Arash, Viehweg, Macsen, Rivera, Mark, Natarajan, Piruthiviraj, Cobos, Everardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818086/
https://www.ncbi.nlm.nih.gov/pubmed/29479542
http://dx.doi.org/10.1177/2324709618758348
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author Venter, Fredrick
Heidari, Arash
Viehweg, Macsen
Rivera, Mark
Natarajan, Piruthiviraj
Cobos, Everardo
author_facet Venter, Fredrick
Heidari, Arash
Viehweg, Macsen
Rivera, Mark
Natarajan, Piruthiviraj
Cobos, Everardo
author_sort Venter, Fredrick
collection PubMed
description Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. A 42-year-old male presented with pain and foul-smelling discharge from his genital warts. The histopathological examination of the mass showed invasive squamous cell carcinoma, and it was associated with paraneoplastic hypercalcemia. The timely removal of long-standing GCA in order to prevent a carcinomatous transition is a priority.
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spelling pubmed-58180862018-02-23 Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia Venter, Fredrick Heidari, Arash Viehweg, Macsen Rivera, Mark Natarajan, Piruthiviraj Cobos, Everardo J Investig Med High Impact Case Rep Case Report Low-risk human papillomavirus types 6 and 11 can manifest as giant condylomata acuminata (GCA) of Buschke-Lowenstein. Up to 50% of GCA can slowly progress over years to fungating, invasive tumors. The malignant potential is attributed to unique immune evading abilities of the human papillomavirus. A 42-year-old male presented with pain and foul-smelling discharge from his genital warts. The histopathological examination of the mass showed invasive squamous cell carcinoma, and it was associated with paraneoplastic hypercalcemia. The timely removal of long-standing GCA in order to prevent a carcinomatous transition is a priority. SAGE Publications 2018-02-15 /pmc/articles/PMC5818086/ /pubmed/29479542 http://dx.doi.org/10.1177/2324709618758348 Text en © 2018 American Federation for Medical Research http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Venter, Fredrick
Heidari, Arash
Viehweg, Macsen
Rivera, Mark
Natarajan, Piruthiviraj
Cobos, Everardo
Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
title Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
title_full Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
title_fullStr Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
title_full_unstemmed Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
title_short Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia
title_sort giant condylomata acuminata of buschke-lowenstein associated with paraneoplastic hypercalcemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818086/
https://www.ncbi.nlm.nih.gov/pubmed/29479542
http://dx.doi.org/10.1177/2324709618758348
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