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The role of conserved residues in Fdc decarboxylase in prenylated flavin mononucleotide oxidative maturation, cofactor isomerization, and catalysis
The UbiD family of reversible decarboxylases act on aromatic, heteroaromatic, and unsaturated aliphatic acids and utilize a prenylated flavin mononucleotide (prFMN) as cofactor, bound adjacent to a conserved Glu–Arg–Glu/Asp ionic network in the enzyme's active site. It is proposed that UbiD act...
Autores principales: | Bailey, Samuel S., Payne, Karl A. P., Fisher, Karl, Marshall, Stephen A., Cliff, Matthew J., Spiess, Reynard, Parker, David A., Rigby, Stephen E. J., Leys, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818171/ https://www.ncbi.nlm.nih.gov/pubmed/29259125 http://dx.doi.org/10.1074/jbc.RA117.000881 |
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