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Galectin-8–mediated selective autophagy protects against seeded tau aggregation

Assembled tau can transfer between cells and seed the aggregation of soluble tau. This process is thought to underlie the amplification and propagation of tau inclusions throughout the brain in neurodegenerative diseases, including Alzheimer's disease. An understanding of the mechanisms involve...

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Detalles Bibliográficos
Autores principales:	Falcon, Benjamin, Noad, Jessica, McMahon, Harvey, Randow, Felix, Goedert, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Neurobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818177/ https://www.ncbi.nlm.nih.gov/pubmed/29282296 http://dx.doi.org/10.1074/jbc.M117.809293

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