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Effects of chondroitin sulfate proteoglycan 4 (NG2/CSPG4) on soft-tissue sarcoma growth depend on tumor developmental stage

Sarcomas, and the mesenchymal precursor cells from which they arise, express chondroitin sulfate proteoglycan 4 (NG2/CSPG4). However, NG2/CSPG4's function and its capacity to serve as a therapeutic target in this tumor type are unknown. Here, we used cells from human tumors and a genetically en...

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Detalles Bibliográficos
Autores principales:	Hsu, Shu-Hsuan Claire, Nadesan, Puviindran, Puviindran, Vijitha, Stallcup, William B., Kirsch, David G., Alman, Benjamin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818183/ https://www.ncbi.nlm.nih.gov/pubmed/29196603 http://dx.doi.org/10.1074/jbc.M117.805051

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