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Tau Filaments and the Development of Positron Emission Tomography Tracers

A pathological pathway leading from soluble, monomeric to insoluble, filamentous Tau, is believed to underlie human Tauopathies. Cases of frontotemporal dementia are caused by dominantly inherited mutations in MAPT, the Tau gene. They show that dysfunction of Tau protein is sufficient to cause neuro...

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Detalles Bibliográficos
Autores principales:	Goedert, Michel, Yamaguchi, Yoshiki, Mishra, Sushil K., Higuchi, Makoto, Sahara, Naruhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818396/ https://www.ncbi.nlm.nih.gov/pubmed/29497399 http://dx.doi.org/10.3389/fneur.2018.00070

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