Cargando…

IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

INTRODUCTION: Murine hepatic NK cells exhibit adaptive features, with liver‐specific adhesion molecules CXCR6 and CD49a acting as surface markers. METHODS: We investigated human liver‐resident CXCR6+ and CD49a+ NK cells using RNA sequencing, flow cytometry, and functional analysis. We further assess...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hydes, Theresa, Noll, Angela, Salinas‐Riester, Gabriela, Abuhilal, Mohammed, Armstrong, Thomas, Hamady, Zaed, Primrose, John, Takhar, Arjun, Walter, Lutz, Khakoo, Salim I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818449/ https://www.ncbi.nlm.nih.gov/pubmed/28952190 http://dx.doi.org/10.1002/iid3.190

Ejemplares similares

Activity of IL-12/15/18 primed natural killer cells against hepatocellular carcinoma
por: Zhuang, Lihui, et al.
Publicado: (2018)

Innate immunity: a new chapter for hepatitis C
por: Hydes, Theresa, et al.
Publicado: (2012)

Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis
por: Hydes, Theresa J., et al.
Publicado: (2019)

IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells
por: Choi, Yeon Ho, et al.
Publicado: (2019)

Human CD49a(+) Lung Natural Killer Cell Cytotoxicity in Response to Influenza A Virus
por: Cooper, Grace E., et al.
Publicado: (2018)

Correction to: IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells
por: Choi, Yeon Ho, et al.
Publicado: (2019)

The proinflammatory cytokines IL-2, IL-15 and IL-21 modulate the repertoire of mature human natural killer cell receptors
por: de Rham, Casimir, et al.
Publicado: (2007)

Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice
por: Koka, Rima, et al.
Publicado: (2003)

Effect of interleukins (IL-2, IL-15, IL-18) on receptors activation and cytotoxic activity of natural killer cells in breast cancer cell
por: Widowati, Wahyu, et al.
Publicado: (2020)

The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by IL-15/IL-15Rα treatment
por: Nair, Savita, et al.
Publicado: (2015)

Sequential Exposure to IL21 and IL15 During Human Natural Killer Cell Expansion Optimizes Yield and Function
por: Zhang, Caimei, et al.
Publicado: (2023)

IL-15/IL-15Rα in SJS/TEN: Relevant Expression of IL15 and IL15RA in Affected Skin
por: Bellón, Teresa, et al.
Publicado: (2022)

Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity
por: Van den Bergh, Johan, et al.
Publicado: (2015)

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor
Publicado: (1994)

Mechanistic Model of Natural Killer Cell Proliferative Response to IL-15 Receptor Stimulation
por: Zhao, Yun M., et al.
Publicado: (2013)

Improving Clinical Manufacturing of IL-15 Activated Cytokine-Induced Killer (CIK) Cells
por: Bremm, Melanie, et al.
Publicado: (2019)

Coordinate Expression and Trans Presentation of Interleukin (IL)-15Rα and IL-15 Supports Natural Killer Cell and Memory CD8(+) T Cell Homeostasis
por: Burkett, Patrick R., et al.
Publicado: (2004)

Natural Killer Cell Subsets and IL-2, IL-15, and IL-18 Genes Expressions in Chronic Kidney Allograft Dysfunction and Graft Function in Kidney Allograft Recipients
por: Assadiasl, S., et al.
Publicado: (2016)

Natural killer cells expanded on membrane-bound IL15 or IL21 activate different miRNA transcriptional profiles with functional consequences
por: Somanchi, Anitha, et al.
Publicado: (2015)

A Chimeric IL-15/IL-15Rα Molecule Expressed on NFκB-Activated Dendritic Cells Supports Their Capability to Activate Natural Killer Cells †
por: Bosch, Naomi C., et al.
Publicado: (2021)

A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma
por: Wagner, Juliane, et al.
Publicado: (2017)

A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells
por: Cubitt, Celia C., et al.
Publicado: (2022)

Mouse hepatitis virus pathogenesis in the central nervous system is independent of IL-15 and natural killer cells
por: Zuo, Jun, et al.
Publicado: (2006)

IL-2, IL-15 and IL-21 expand T cells for targeted adoptive therapy
por: Liu, Zhenjiang, et al.
Publicado: (2015)

Electrotransfer of IL-15/IL-15Rα complex for the treatment of established melanoma
por: Shirley, Shawna, et al.
Publicado: (2015)

An activation-induced IL-15 isoform is a natural antagonist for IL-15 function
por: Zhao, Lei, et al.
Publicado: (2016)

Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma
por: Shirley, Shawna A., et al.
Publicado: (2020)

IL-4 and IL-4 Receptor Expression Is Dispensable for the Development and Function of Natural Killer T Cells
por: Sharma, Archna, et al.
Publicado: (2013)

Immunomodulation with IL-7 and IL-15 in HIV-1 infection
por: Gunst, Jesper D., et al.
Publicado: (2023)

IL-2/IL-15 activate the human clonally-restricted KIR3DL1 reverse promoter
por: Presnell, Steven R., et al.
Publicado: (2013)

Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy
por: Zhang, Ying, et al.
Publicado: (2022)

Expansion of invariant natural killer T cells from systemic lupus erythematosus patients by alpha-Galactosylceramide and IL-15
por: Hsu, Chien-Ya, et al.
Publicado: (2021)

PDGF-D−PDGFRβ signaling enhances IL-15–mediated human natural killer cell survival
por: Ma, Shoubao, et al.
Publicado: (2022)

Off-the-shelf CAR natural killer cells secreting IL-15 target spike in treating COVID-19
por: Lu, Ting, et al.
Publicado: (2022)

Lineage Relationships and Differentiation of Natural Killer (NK) T Cells: Intrathymic Selection and Interleukin (IL)-4 Production in the Absence of NKR-P1 and Ly49 Molecules
por: Lantz, Olivier, et al.
Publicado: (1997)

IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity
por: Warner, Sophie C., et al.
Publicado: (2020)

IL-15 Enhances the Persistence and Function of BCMA-Targeting CAR-T Cells Compared to IL-2 or IL-15/IL-7 by Limiting CAR-T Cell Dysfunction and Differentiation
por: Battram, Anthony M., et al.
Publicado: (2021)

Antigens of Mycobacterium tuberculosis Stimulate CXCR6+ Natural Killer Cells
por: Choreño-Parra, José Alberto, et al.
Publicado: (2020)

Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs
por: Neves, Fabiana, et al.
Publicado: (2015)

Effect of IL-7 and IL-15 on T cell phenotype in myelodysplastic syndromes
por: Dong, Wen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iv12n6jsso6v8307jtemtsk59a