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Interleukin (IL)-6 Inhibits IL-27- and IL-30-Mediated Inflammatory Responses in Human Monocytes

Interleukin (IL)-30, the IL-27p28 subunit of the heterodimeric cytokine IL-27, acts as an antagonist of IL-27 and IL-6 signaling in murine cells via glycoprotein 130 (gp130) receptor and additional binding partners. Thus far, functions of IL-30 have not been fully elucidated in human cells. We demon...

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Detalles Bibliográficos
Autores principales:	Petes, Carlene, Mariani, Mélissa K., Yang, Yawen, Grandvaux, Nathalie, Gee, Katrina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818456/ https://www.ncbi.nlm.nih.gov/pubmed/29497424 http://dx.doi.org/10.3389/fimmu.2018.00256

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