A dual-mode mobile phone microscope using the onboard camera flash and ambient light

Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing...

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Detalles Bibliográficos
Autores principales: Orth, A., Wilson, E. R., Thompson, J. G., Gibson, B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818495/
https://www.ncbi.nlm.nih.gov/pubmed/29459650
http://dx.doi.org/10.1038/s41598-018-21543-2
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author Orth, A.
Wilson, E. R.
Thompson, J. G.
Gibson, B. C.
author_facet Orth, A.
Wilson, E. R.
Thompson, J. G.
Gibson, B. C.
author_sort Orth, A.
collection PubMed
description Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing complexity whilst maintaining functionality and performance. The microscope is capable of both brightfield and darkfield imaging modes, enabling microscopic visualisation of samples ranging from plant to mammalian cells. We describe the microscope design principles, assembly process, and demonstrate its imaging capabilities through the visualisation of unlabelled cell nuclei to observing the motility of cattle sperm and zooplankton.
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spelling pubmed-58184952018-02-26 A dual-mode mobile phone microscope using the onboard camera flash and ambient light Orth, A. Wilson, E. R. Thompson, J. G. Gibson, B. C. Sci Rep Article Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing complexity whilst maintaining functionality and performance. The microscope is capable of both brightfield and darkfield imaging modes, enabling microscopic visualisation of samples ranging from plant to mammalian cells. We describe the microscope design principles, assembly process, and demonstrate its imaging capabilities through the visualisation of unlabelled cell nuclei to observing the motility of cattle sperm and zooplankton. Nature Publishing Group UK 2018-02-19 /pmc/articles/PMC5818495/ /pubmed/29459650 http://dx.doi.org/10.1038/s41598-018-21543-2 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Orth, A.
Wilson, E. R.
Thompson, J. G.
Gibson, B. C.
A dual-mode mobile phone microscope using the onboard camera flash and ambient light
title A dual-mode mobile phone microscope using the onboard camera flash and ambient light
title_full A dual-mode mobile phone microscope using the onboard camera flash and ambient light
title_fullStr A dual-mode mobile phone microscope using the onboard camera flash and ambient light
title_full_unstemmed A dual-mode mobile phone microscope using the onboard camera flash and ambient light
title_short A dual-mode mobile phone microscope using the onboard camera flash and ambient light
title_sort dual-mode mobile phone microscope using the onboard camera flash and ambient light
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818495/
https://www.ncbi.nlm.nih.gov/pubmed/29459650
http://dx.doi.org/10.1038/s41598-018-21543-2
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