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A single NaK channel conformation is not enough for non-selective ion conduction
NaK and other non-selective channels are able to conduct both sodium (Na(+)) and potassium (K(+)) with equally high efficiency. In contrast to previous crystallographic results, we show that the selectivity filter (SF) of NaK in native-like lipid membranes adopts two distinct conformations that are...
Autores principales: | Shi, Chaowei, He, Yao, Hendriks, Kitty, de Groot, Bert L., Cai, Xiaoying, Tian, Changlin, Lange, Adam, Sun, Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818664/ https://www.ncbi.nlm.nih.gov/pubmed/29459730 http://dx.doi.org/10.1038/s41467-018-03179-y |
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