Cargando…

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin

Human skin harbors two major T cell compartments of equal size that are distinguished by expression of the chemokine receptor CCR8. In vitro studies have demonstrated that CCR8 expression is regulated by TCR engagement and the skin tissue microenvironment. To extend these observations, we examined t...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCully, Michelle L., Ladell, Kristin, Andrews, Robert, Jones, Rhiannon E., Miners, Kelly L., Roger, Laureline, Baird, Duncan M., Cameron, Mark J., Jessop, Zita M., Whitaker, Iain S., Davies, Eleri L., Price, David A., Moser, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2018
Materias:	Immune Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818732/ https://www.ncbi.nlm.nih.gov/pubmed/29427415 http://dx.doi.org/10.4049/jimmunol.1701377

Ejemplares similares

Bovine γδ T Cells Are a Major Regulatory T Cell Subset
por: Guzman, Efrain, et al.
Publicado: (2014)

Engulfment of Activated Apoptotic Cells Abolishes TGF-β–Mediated Immunoregulation via the Induction of IL-6
por: Notley, Clare A., et al.
Publicado: (2015)

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation
por: Stark, Anne-Katrien, et al.
Publicado: (2020)

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes
por: Dee, Christopher T., et al.
Publicado: (2016)

Zebrafish IL-4–like Cytokines and IL-10 Suppress Inflammation but Only IL-10 Is Essential for Gill Homeostasis
por: Bottiglione, Federica, et al.
Publicado: (2020)

IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4(+) T Cells
por: Ridley, Michael L., et al.
Publicado: (2020)

The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation
por: Xie, Bin, et al.
Publicado: (2021)

T cell memory revisited using single telomere length analysis
por: Roger, Laureline, et al.
Publicado: (2023)

IL-21 Promotes CD4 T Cell Responses by Phosphatidylinositol 3-Kinase–Dependent Upregulation of CD86 on B Cells
por: Attridge, Kesley, et al.
Publicado: (2014)

Podocytes Regulate Neutrophil Recruitment by Glomerular Endothelial Cells via IL-6–Mediated Crosstalk
por: Kuravi, Sahithi J., et al.
Publicado: (2014)

1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept
por: Gardner, David H., et al.
Publicado: (2015)

Long-Lived CD4(+)IFN-γ(+) T Cells rather than Short-Lived CD4(+)IFN-γ(+)IL-10(+) T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection
por: Villegas-Mendez, Ana, et al.
Publicado: (2016)

T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System
por: Huang, Wei-Chen, et al.
Publicado: (2017)

A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4
por: Jafarnejad, Mohammad, et al.
Publicado: (2017)

The Small Rho GTPase TC10 Modulates B Cell Immune Responses
por: Burbage, Marianne, et al.
Publicado: (2017)

Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells
por: Hewitson, James P., et al.
Publicado: (2020)

RUNX1 Regulates a Transcription Program That Affects the Dynamics of Cell Cycle Entry of Naive Resting B Cells
por: Thomsen, Inesa, et al.
Publicado: (2021)

The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk
por: Clement, Dennis, et al.
Publicado: (2023)

Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
por: Cowan, Jennifer E., et al.
Publicado: (2014)

SARS‐CoV2 pneumonia recovery is linked to expansion of innate lymphoid cells type 2 expressing CCR10
por: Gomes, André M. C., et al.
Publicado: (2021)

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux
por: Ahmed, Raya, et al.
Publicado: (2016)

The Human Cutaneous Chemokine System
por: McCully, Michelle L., et al.
Publicado: (2011)

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4(+) T cells independently of CCR6
por: Taylor, Karen, et al.
Publicado: (2009)

Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS‐CoV‐2 infection
por: Spoerl, Silvia, et al.
Publicado: (2021)

Avidity of influenza-specific memory CD8(+) T-cell populations decays over time compromising antiviral immunity
por: Humphreys, Ian R, et al.
Publicado: (2012)

Human T(SCM) cell dynamics in vivo are compatible with long-lived immunological memory and stemness
por: Costa del Amo, Pedro, et al.
Publicado: (2018)

CD57(+) Memory T Cells Proliferate In Vivo
por: Ahmed, Raya, et al.
Publicado: (2020)

CCL5-armed oncolytic virus augments CCR5-engineered NK cell infiltration and antitumor efficiency
por: Li, Feng, et al.
Publicado: (2020)

CD5 levels define functionally heterogeneous populations of naïve human CD4(+) T cells
por: Sood, Aditi, et al.
Publicado: (2021)

Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells
por: McCully, Michelle L., et al.
Publicado: (2015)

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7(+) Progenitors to the Thymus
por: Cosway, Emilie J., et al.
Publicado: (2018)

Expression of IL‐7Rα and KLRG1 defines functionally distinct CD8(+) T‐cell populations in humans
por: Remmerswaal, Ester B. M., et al.
Publicado: (2019)

CD28 and CD57 define four populations with distinct phenotypic properties within human CD8(+) T cells
por: Pangrazzi, Luca, et al.
Publicado: (2019)

Mouse Memory CD8 T Cell Subsets Defined by Tissue-Resident Memory Integrin Expression Exhibit Distinct Metabolic Profiles
por: Sportiello, Mike, et al.
Publicado: (2023)

Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection
por: Polcz, Valerie E., et al.
Publicado: (2023)

Defining the Mechanistic Correlates of Protection Conferred by Whole-Cell Vaccination against Pseudomonas aeruginosa Acute Murine Pneumonia
por: Sen-Kilic, Emel, et al.
Publicado: (2021)

Defining the Glycosaminoglycan Interactions of Complement Factor H–Related Protein 5
por: Gyapon-Quast, Frederick, et al.
Publicado: (2021)

Functional assays to screen and select monoclonal antibodies that target Yersinia pestis
por: Biryukov, Sergei S., et al.
Publicado: (2023)

Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity
por: Giles, James A, et al.
Publicado: (2015)

Acute-Phase CD8 T Cell Responses That Select for Escape Variants Are Needed to Control Live Attenuated Simian Immunodeficiency Virus
por: Harris, Max, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_moohh4oi19n02gdea93c3d222o