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Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute

PURPOSE: To determine the indications, long-term clinical and visual outcomes, and complications of the aphakic snap-on type I Boston keratoprosthesis (KPro). DESIGN: Retrospective, non-comparative case series. METHODS: Forty-five eyes of 43 patients with type I aphakic snap-on KPros with at least 1...

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Autores principales: Gibbons, Allister, Leung, Ella H, Haddock, Luis J, Medina, Carlos A, Fernandez, Viviana, Parel, Jean-Marie A, Durkee, Heather A, Amescua, Guillermo, Alfonso, Eduardo C, Perez, Victor L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818861/
https://www.ncbi.nlm.nih.gov/pubmed/29497273
http://dx.doi.org/10.2147/OPTH.S144403
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author Gibbons, Allister
Leung, Ella H
Haddock, Luis J
Medina, Carlos A
Fernandez, Viviana
Parel, Jean-Marie A
Durkee, Heather A
Amescua, Guillermo
Alfonso, Eduardo C
Perez, Victor L
author_facet Gibbons, Allister
Leung, Ella H
Haddock, Luis J
Medina, Carlos A
Fernandez, Viviana
Parel, Jean-Marie A
Durkee, Heather A
Amescua, Guillermo
Alfonso, Eduardo C
Perez, Victor L
author_sort Gibbons, Allister
collection PubMed
description PURPOSE: To determine the indications, long-term clinical and visual outcomes, and complications of the aphakic snap-on type I Boston keratoprosthesis (KPro). DESIGN: Retrospective, non-comparative case series. METHODS: Forty-five eyes of 43 patients with type I aphakic snap-on KPros with at least 1 year of follow-up were included. The past medical histories, preoperative indications, best-corrected visual acuities (BCVAs), postoperative complications, and retention rates were analyzed. RESULTS: The most common indication for KPro implantation was a failed corneal graft (89%). The mean preoperative BCVA was count fingers–hand motion (2.14±0.45 logarithm of minimum angle of resolution [logMAR]), which initially improved to 20/200 (1.04±0.85 logMAR; P<0.0001). At the last examination, 24 eyes (53%) maintained some visual gain, 22% retained their preoperative visual acuity, and 24% lost vision due to postoperative events and underlying ocular comorbidities. Postoperative complications included retroprosthetic membranes (8/45, 18%), corneal melts (5/45, 11%), glaucoma progression (6/45, 13%), and endophthalmitis or sterile vitritis (6/45, 13%). The KPro retention rate was 89%, with a mean follow-up of 51 months. The mean BCVA at the last visit was 20/1,400 (1.82±0.92 logMAR). CONCLUSION: Most patients experienced improved visual acuity after the implantation of the aphakic, snap-on type I KPro; however, the visual gains were not sustained over time, correlating with the onset of postoperative complications.
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spelling pubmed-58188612018-03-01 Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute Gibbons, Allister Leung, Ella H Haddock, Luis J Medina, Carlos A Fernandez, Viviana Parel, Jean-Marie A Durkee, Heather A Amescua, Guillermo Alfonso, Eduardo C Perez, Victor L Clin Ophthalmol Original Research PURPOSE: To determine the indications, long-term clinical and visual outcomes, and complications of the aphakic snap-on type I Boston keratoprosthesis (KPro). DESIGN: Retrospective, non-comparative case series. METHODS: Forty-five eyes of 43 patients with type I aphakic snap-on KPros with at least 1 year of follow-up were included. The past medical histories, preoperative indications, best-corrected visual acuities (BCVAs), postoperative complications, and retention rates were analyzed. RESULTS: The most common indication for KPro implantation was a failed corneal graft (89%). The mean preoperative BCVA was count fingers–hand motion (2.14±0.45 logarithm of minimum angle of resolution [logMAR]), which initially improved to 20/200 (1.04±0.85 logMAR; P<0.0001). At the last examination, 24 eyes (53%) maintained some visual gain, 22% retained their preoperative visual acuity, and 24% lost vision due to postoperative events and underlying ocular comorbidities. Postoperative complications included retroprosthetic membranes (8/45, 18%), corneal melts (5/45, 11%), glaucoma progression (6/45, 13%), and endophthalmitis or sterile vitritis (6/45, 13%). The KPro retention rate was 89%, with a mean follow-up of 51 months. The mean BCVA at the last visit was 20/1,400 (1.82±0.92 logMAR). CONCLUSION: Most patients experienced improved visual acuity after the implantation of the aphakic, snap-on type I KPro; however, the visual gains were not sustained over time, correlating with the onset of postoperative complications. Dove Medical Press 2018-02-15 /pmc/articles/PMC5818861/ /pubmed/29497273 http://dx.doi.org/10.2147/OPTH.S144403 Text en © 2018 Gibbons et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Gibbons, Allister
Leung, Ella H
Haddock, Luis J
Medina, Carlos A
Fernandez, Viviana
Parel, Jean-Marie A
Durkee, Heather A
Amescua, Guillermo
Alfonso, Eduardo C
Perez, Victor L
Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute
title Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute
title_full Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute
title_fullStr Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute
title_full_unstemmed Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute
title_short Long-term outcomes of the aphakic snap-on Boston type I keratoprosthesis at the Bascom Palmer Eye Institute
title_sort long-term outcomes of the aphakic snap-on boston type i keratoprosthesis at the bascom palmer eye institute
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818861/
https://www.ncbi.nlm.nih.gov/pubmed/29497273
http://dx.doi.org/10.2147/OPTH.S144403
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