Cargando…
Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output
Though the seasonal response of organisms to changing day lengths is a phenomenon that has been scientifically reported for nearly a century, significant questions remain about how photoperiod is encoded and effected neurobiologically. In mammals, early work identified the master circadian clock, th...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818903/ https://www.ncbi.nlm.nih.gov/pubmed/29552032 http://dx.doi.org/10.1155/2018/8217345 |
_version_ | 1783301105381277696 |
---|---|
author | Tackenberg, Michael C. McMahon, Douglas G. |
author_facet | Tackenberg, Michael C. McMahon, Douglas G. |
author_sort | Tackenberg, Michael C. |
collection | PubMed |
description | Though the seasonal response of organisms to changing day lengths is a phenomenon that has been scientifically reported for nearly a century, significant questions remain about how photoperiod is encoded and effected neurobiologically. In mammals, early work identified the master circadian clock, the suprachiasmatic nuclei (SCN), as a tentative encoder of photoperiodic information. Here, we provide an overview of research on the SCN as a coordinator of photoperiodic responses, the intercellular coupling changes that accompany that coordination, as well as the SCN's role in a putative brain network controlling photoperiodic input and output. Lastly, we discuss the importance of photoperiodic research in the context of tangible benefits to human health that have been realized through this research as well as challenges that remain. |
format | Online Article Text |
id | pubmed-5818903 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58189032018-03-18 Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output Tackenberg, Michael C. McMahon, Douglas G. Neural Plast Review Article Though the seasonal response of organisms to changing day lengths is a phenomenon that has been scientifically reported for nearly a century, significant questions remain about how photoperiod is encoded and effected neurobiologically. In mammals, early work identified the master circadian clock, the suprachiasmatic nuclei (SCN), as a tentative encoder of photoperiodic information. Here, we provide an overview of research on the SCN as a coordinator of photoperiodic responses, the intercellular coupling changes that accompany that coordination, as well as the SCN's role in a putative brain network controlling photoperiodic input and output. Lastly, we discuss the importance of photoperiodic research in the context of tangible benefits to human health that have been realized through this research as well as challenges that remain. Hindawi 2018-01-09 /pmc/articles/PMC5818903/ /pubmed/29552032 http://dx.doi.org/10.1155/2018/8217345 Text en Copyright © 2018 Michael C. Tackenberg and Douglas G. McMahon. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Tackenberg, Michael C. McMahon, Douglas G. Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output |
title | Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output |
title_full | Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output |
title_fullStr | Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output |
title_full_unstemmed | Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output |
title_short | Photoperiodic Programming of the SCN and Its Role in Photoperiodic Output |
title_sort | photoperiodic programming of the scn and its role in photoperiodic output |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818903/ https://www.ncbi.nlm.nih.gov/pubmed/29552032 http://dx.doi.org/10.1155/2018/8217345 |
work_keys_str_mv | AT tackenbergmichaelc photoperiodicprogrammingofthescnanditsroleinphotoperiodicoutput AT mcmahondouglasg photoperiodicprogrammingofthescnanditsroleinphotoperiodicoutput |