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Time-Dependent Effects of POT1 Knockdown on Proliferation, Tumorigenicity, and HDACi Response of SK-OV3 Ovarian Cancer Cells

The roles of protection of telomeres 1 (POT1) in human ovarian cancer have not been fully elucidated. Here, we investigated the impact of POT1 knockdown (POT1-KD) on in vitro cell proliferation, tumorigenesis, and histone deacetylase inhibitor (HDACi) response in human ovarian cancer-derived SK-OV3...

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Detalles Bibliográficos
Autores principales: Zhou, Hua, Mondal, Abdul, Dakic, Aleksandra, Alhawas, Lama, Liu, Xuefeng, He, Zhixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818924/
https://www.ncbi.nlm.nih.gov/pubmed/29546066
http://dx.doi.org/10.1155/2018/7184253