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Inhibition of coxsackievirus infection in cardiomyocytes by small dsRNA targeting its cognate coxsackievirus adenovirus receptor

BACKGROUND & OBJECTIVES: Coxsackievirus B (CVB), a member of human Enterovirus group, is the most common cause of viral myocarditis. Coxsackievirus adenovirus receptor (CAR) is identified as a key determinant for the entry of CVB in the target cells. Thus, blockade of receptor by RNA interferenc...

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Detalles Bibliográficos
Autores principales: Sharma, Mirnalini, Mishra, Baijayantimala, Saikia, Uma Nahar, Bahl, Ajay, Ratho, R. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819035/
https://www.ncbi.nlm.nih.gov/pubmed/29434067
http://dx.doi.org/10.4103/ijmr.IJMR_761_15

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