Central Precocious Puberty – Management and Long-term Outcomes

Central precocious puberty (CPP) results from premature re-activation of the gonadotropic axis. CPP is much more common in girls than in boys and is idiopathic in most cases. In boys, precocious puberty is more likely to be linked to hypothalamic lesions (≈40%). Recent studies have implicated the in...

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Detalles Bibliográficos
Autores principales: Léger, Juliane, Carel, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Touch Medical Media 2015
Materias:
Paediatric Endocrinology Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819064/
https://www.ncbi.nlm.nih.gov/pubmed/29632569
http://dx.doi.org/10.17925/EE.2015.11.01.45
Descripción
Sumario:Central precocious puberty (CPP) results from premature re-activation of the gonadotropic axis. CPP is much more common in girls than in boys and is idiopathic in most cases. In boys, precocious puberty is more likely to be linked to hypothalamic lesions (≈40%). Recent studies have implicated the inactivation of MKRN3 gene in ‘idiopathic’ CPP Gonadotropin-releasing hormone agonists are the standard treatment for progressive CPP.

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