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Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

BACKGROUND: Epigenetic regulators are frequently mutated or aberrantly expressed in a variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, and response to therapy. RESULTS: To define alterations in epigenetic landscapes in breast cancers, we...

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Detalles Bibliográficos
Autores principales: Xi, Yuanxin, Shi, Jiejun, Li, Wenqian, Tanaka, Kaori, Allton, Kendra L., Richardson, Dana, Li, Jing, Franco, Hector L., Nagari, Anusha, Malladi, Venkat S., Coletta, Luis Della, Simper, Melissa S., Keyomarsi, Khandan, Shen, Jianjun, Bedford, Mark T., Shi, Xiaobing, Barton, Michelle C., Kraus, W. Lee, Li, Wei, Dent, Sharon Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819162/
https://www.ncbi.nlm.nih.gov/pubmed/29458327
http://dx.doi.org/10.1186/s12864-018-4533-0