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Cooperative p16 and p21 action protects female astrocytes from transformation

Mechanisms underlying sex differences in cancer incidence are not defined but likely involve dimorphism (s) in tumor suppressor function at the cellular and organismal levels. As an example, sexual dimorphism in retinoblastoma protein (Rb) activity was shown to block transformation of female, but no...

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Detalles Bibliográficos
Autores principales:	Kfoury, Najla, Sun, Tao, Yu, Kwanha, Rockwell, Nathan, Tinkum, Kelsey L., Qi, Zongtai, Warrington, Nicole M., McDonald, Peter, Roy, Anuradha, Weir, Scott J., Mohila, Carrie A., Deneen, Benjamin, Rubin, Joshua B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819173/ https://www.ncbi.nlm.nih.gov/pubmed/29458417 http://dx.doi.org/10.1186/s40478-018-0513-5

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