Cargando…

HMGB2 is associated with malignancy and regulates Warburg effect by targeting LDHB and FBP1 in breast cancer

BACKGROUND: High-mobility group box 2 (HMGB2) is implicated in tumorigenesis in various cancers. However, the clinical significance of HMGB2 signaling in human breast cancer progression remains unknown. METHODS: We investigated HMGB2 expression in 185 cases of primary breast cancer and matched norma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Deyuan, Li, Jing, Wei, Jinli, Zhang, Zhengquan, Luo, Yulin, Tan, Haosheng, Ren, Chuanli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819211/ https://www.ncbi.nlm.nih.gov/pubmed/29463261 http://dx.doi.org/10.1186/s12964-018-0219-0

Ejemplares similares

Sox17 Promoter Methylation in Plasma DNA Is Associated With Poor Survival and Can Be Used as a Prognostic Factor in Breast Cancer
por: Fu, Deyuan, et al.
Publicado: (2015)

miR-517a promotes Warburg effect in HCC by directly targeting FBP1
por: Zhang, Delin, et al.
Publicado: (2018)

MAGE-TRIM28 complex promotes the Warburg effect and hepatocellular carcinoma progression by targeting FBP1 for degradation
por: Jin, X, et al.
Publicado: (2017)

MiR-141-3p overexpression suppresses the malignancy of osteosarcoma by targeting FUS to degrade LDHB
por: Wang, Lei
Publicado: (2020)

PTEN loss promotes Warburg effect and prostate cancer cell growth by inducing FBP1 degradation
por: Song, Changze, et al.
Publicado: (2022)

Early and late outcomes of bevacizumab plus chemotherapy versus chemotherapy alone as a neoadjuvant treatment in HER2-negative nonmetastatic breast cancer: a meta-analysis of randomized controlled trials
por: Wei, Jinli, et al.
Publicado: (2018)

Slc2a6 regulates myoblast differentiation by targeting LDHB
por: Jiang, Xuan, et al.
Publicado: (2022)

Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia
por: Xu, Yi, et al.
Publicado: (2022)

The Reverse Warburg Effect Is Associated with Fbp2-Dependent Hif1α Regulation in Cancer Cells Stimulated by Fibroblasts
por: Duda, Przemysław, et al.
Publicado: (2020)

Correction: Vitamin D activates FBP1 to block the Warburg effect and modulate blast metabolism in acute myeloid leukemia
por: Xu, Yi, et al.
Publicado: (2022)

The KLF14 Transcription Factor Regulates Glycolysis by Downregulating LDHB in Colorectal Cancer
por: Wu, Guiyang, et al.
Publicado: (2019)

FBP1 /miR-24-1/enhancer axis activation blocks renal cell carcinoma progression via Warburg effect
por: Ju, Dongen, et al.
Publicado: (2022)

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells
por: Urbańska, Kaja, et al.
Publicado: (2019)

LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid
por: Decking, Sonja-Maria, et al.
Publicado: (2022)

PKM2 Regulates the Warburg Effect and Promotes HMGB1 Release in Sepsis
por: Yang, Liangchun, et al.
Publicado: (2014)

Loss of fibulin-2 expression is involved in the inhibition of breast cancer invasion and forms a new barrier in addition to the basement membrane
por: Tan, Haosheng, et al.
Publicado: (2017)

SIRT5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
por: Shi, Liang, et al.
Publicado: (2018)

FBP1 expression is associated with basal-like breast carcinoma
por: Shi, Lei, et al.
Publicado: (2017)

Low Expression of LDHB Correlates With Unfavorable Survival in Hepatocellular Carcinoma: Strobe-Compliant Article
por: Chen, Ruohua, et al.
Publicado: (2015)

Suppressed expression of LDHB promotes age-related hearing loss via aerobic glycolysis
por: Tian, Chunjie, et al.
Publicado: (2020)

Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions
por: Booth, Charles E., et al.
Publicado: (2022)

Parallel Implementation of Katsevich's FBP Algorithm
por: Yang, Jiansheng, et al.
Publicado: (2006)

FBP1 Is an Interacting Partner of Menin
por: Zaman, Shadia, et al.
Publicado: (2014)

LDHB Deficiency Promotes Mitochondrial Dysfunction Mediated Oxidative Stress and Neurodegeneration in Adult Mouse Brain
por: Park, Jun Sung, et al.
Publicado: (2022)

Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect
por: Cheng, Aoxing, et al.
Publicado: (2019)

HYOU1 facilitates proliferation, invasion and glycolysis of papillary thyroid cancer via stabilizing LDHB mRNA
por: Wang, Jia‐Mei, et al.
Publicado: (2021)

FBP1 promotes ovarian cancer development through the acceleration of cell cycle transition and metastasis
por: Xiong, Xifeng, et al.
Publicado: (2018)

The FUSE binding proteins FBP1 and FBP3 are potential c-myc regulators in renal, but not in prostate and bladder cancer
por: Weber, Achim, et al.
Publicado: (2008)

A Novel Iterative CT Reconstruction Approach Based on FBP Algorithm
por: Shi, Hongli, et al.
Publicado: (2015)

MiR-375 Regulation of LDHB Plays Distinct Roles in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma
por: Kumar, Satendra, et al.
Publicado: (2018)

The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma
por: Chen, Jie, et al.
Publicado: (2023)

Deubiquitination of FBP1 by USP7 blocks FBP1–DNMT1 interaction and decreases the sensitivity of pancreatic cancer cells to PARP inhibitors
por: Cheng, Xiang, et al.
Publicado: (2021)

A novel scheme to design the filter for CT reconstruction using FBP algorithm
por: Shi, Hongli, et al.
Publicado: (2013)

Synchronous primary cancers of the thyroid and breast: A case report and review of the literature
por: LIU, LI, et al.
Publicado: (2015)

A study of the interaction space of two lactate dehydrogenase isoforms (LDHA and LDHB) and some of their inhibitors using proteochemometrics modeling
por: Damavandi, Sedigheh, et al.
Publicado: (2023)

Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer
por: Gonzalez, Claudio D., et al.
Publicado: (2014)

An Apoptotic and Endosymbiotic Explanation of the Warburg and the Inverse Warburg Hypotheses
por: Kaczanowski, Szymon, et al.
Publicado: (2018)

FBP1 induced by β‐elemene enhances the sensitivity of gefitinib in lung cancer
por: Li, Jian, et al.
Publicado: (2022)

HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma
por: Wang, Yanbin, et al.
Publicado: (2019)

Expression and Prognostic Value of miR-486-5p in Patients with Gastric Adenocarcinoma
por: Chen, Hui, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_nj5i4kfnvhkjsesu5s0k46p9vd