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FAK-ERK activation in cell/matrix adhesion induced by the loss of apolipoprotein E stimulates the malignant progression of ovarian cancer

BACKGROUND: Extracellular matrix (ECM) is a mediator of tumor progression. However, whether the alterations of the intraperitoneal ECM prior to tumor establishment affects the malignant progression of ovarian cancer remains elusive. METHODS: Apolipoprotein (ApoE) knock-out mice was used to analyze t...

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Detalles Bibliográficos
Autores principales: Lai, Huiling, Zhao, Xuejiao, Qin, Yu, Ding, Yi, Chen, Ruqi, Li, Guannan, Labrie, Marilyne, Ding, Zhiyong, Zhou, Jianfeng, Hu, Junbo, Ma, Ding, Fang, Yong, Gao, Qinglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819228/
https://www.ncbi.nlm.nih.gov/pubmed/29458390
http://dx.doi.org/10.1186/s13046-018-0696-4

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