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Characterization and heterologous expression of the neoabyssomicin/abyssomicin biosynthetic gene cluster from Streptomyces koyangensis SCSIO 5802

BACKGROUND: The deep-sea-derived microbe Streptomyces koyangensis SCSIO 5802 produces neoabyssomicins A–B (1–2) and abyssomicins 2 (3) and 4 (4). Neoabyssomicin A (1) augments human immunodeficiency virus-1 (HIV-1) replication whereas abyssomicin 2 (3) selectively reactivates latent HIV and is also...

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Detalles Bibliográficos
Autores principales:	Tu, Jiajia, Li, Siting, Chen, Jiang, Song, Yongxiang, Fu, Shaobin, Ju, Jianhua, Li, Qinglian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819245/ https://www.ncbi.nlm.nih.gov/pubmed/29463238 http://dx.doi.org/10.1186/s12934-018-0875-1

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