Cargando…

Depletion of membrane cholesterol compromised caspase-8 imparts in autophagy induction and inhibition of cell migration in cancer cells

BACKGROUND: Cholesterol in lipid raft plays crucial role on cancer cell survival during metastasis of cancer cells. Cancer cells are reported to enrich cholesterol in lipid raft which make them more susceptible to cell death after cholesterol depletion than normal cells. Methyl-β-cyclodextrin (MβCD)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Mukesh, Irungbam, Karuna, Kataria, Meena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819249/ https://www.ncbi.nlm.nih.gov/pubmed/29467593 http://dx.doi.org/10.1186/s12935-018-0520-4

Ejemplares similares

Caspase-2 is involved in cell death induction by taxanes in breast cancer cells
por: Jelínek, Michael, et al.
Publicado: (2013)

The role of individual caspases in cell death induction by taxanes in breast cancer cells
por: Jelínek, Michael, et al.
Publicado: (2015)

Depleting NFAT1 expression inhibits the ability of invasion and migration of human lung cancer cells
por: Liu, Ji-fu, et al.
Publicado: (2013)

The anticancer effects of ferulic acid is associated with induction of cell cycle arrest and autophagy in cervical cancer cells
por: Gao, Jinhua, et al.
Publicado: (2018)

Functional disruption of macrophage migration inhibitory factor (MIF) suppresses proliferation of human H460 lung cancer cells by caspase-dependent apoptosis
por: Guo, Yubiao, et al.
Publicado: (2013)

Liver X receptor activation induces apoptosis of melanoma cell through caspase pathway
por: Zhang, Wenjun, et al.
Publicado: (2014)

Inhibitor of caspase-activated DNase expression enhances caspase-activated DNase expression and inhibits oxidative stress-induced chromosome breaks at the mixed lineage leukaemia gene in nasopharyngeal carcinoma cells
por: Boon, Siaw Shi, et al.
Publicado: (2015)

Compromised base excision repair pathway in Mycobacterium tuberculosis imparts superior adaptability in the host
por: Naz, Saba, et al.
Publicado: (2021)

MicroRNA-1182 and let-7a exert synergistic inhibition on invasion, migration and autophagy of cholangiocarcinoma cells through down-regulation of NUAK1
por: Pan, Xin, et al.
Publicado: (2021)

MAP7 promotes migration and invasion and progression of human cervical cancer through modulating the autophagy
por: Zhang, Li, et al.
Publicado: (2020)

Autologous stem-cell transplantation in refractory autoimmune diseases after in vivo immunoablation and ex vivo depletion of mononuclear cells
por: Rosen, Oliver, et al.
Publicado: (2000)

Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death
por: Baumert, Hannah Maria, et al.
Publicado: (2020)

Polyamine depletion induces G(1 )and S phase arrest in human retinoblastoma Y79 cells
por: Ueda, Akiko, et al.
Publicado: (2008)

CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death
por: Chung, Alexander H., et al.
Publicado: (2019)

BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells
por: Johnson, Nicole C, et al.
Publicado: (2002)

Biomarkers to quantify cell migration characteristics
por: Kwon, Sangwoo, et al.
Publicado: (2020)

The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells
por: Raza, Shaneabbas, et al.
Publicado: (2017)

Upregulation of death receptor 5 and activation of caspase 8/3 play a critical role in ergosterol peroxide induced apoptosis in DU 145 prostate cancer cells
por: Han, Jonghyun, et al.
Publicado: (2014)

Matrine inhibits cell growth, migration, invasion and promotes autophagy in hepatocellular carcinoma by regulation of circ_0027345/miR-345-5p/HOXD3 axis
por: Lin, Shaobing, et al.
Publicado: (2020)

Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro
por: Zhang, Junping, et al.
Publicado: (2014)

Increased toxicity of a trinuclear Pt-compound in a human squamous carcinoma cell line by polyamine depletion
por: Oredsson, Stina M, et al.
Publicado: (2012)

MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC
por: Chen, Tian-Jun, et al.
Publicado: (2021)

Depleting TMED3 alleviates the development of endometrial carcinoma
por: Zhang, Jin, et al.
Publicado: (2022)

Styrylpyrone Derivative (SPD) induces apoptosis in a caspase-7-dependent manner in the human breast cancer cell line MCF-7
por: Lee, Alvin Teck Chien, et al.
Publicado: (2003)

Glutamate involvement in calcium–dependent migration of astrocytoma cells
por: Hamadi, Abdelkader, et al.
Publicado: (2014)

BORA regulates cell proliferation and migration in bladder cancer
por: Cheng, Songtao, et al.
Publicado: (2020)

Overexpression of FES might inhibit cell proliferation, migration, and invasion of osteosarcoma cells
por: Zhao, Yang, et al.
Publicado: (2020)

Metformin impairs growth of endometrial cancer cells via cell cycle arrest and concomitant autophagy and apoptosis
por: Takahashi, Akimasa, et al.
Publicado: (2014)

Exploitation of necroptosis for treatment of caspase-compromised cancers
por: Cho, Young Sik, et al.
Publicado: (2017)

Selective migration of neuralized embryonic stem cells to stem cell factor and media conditioned by glioma cell lines
por: Serfozo, Peter, et al.
Publicado: (2006)

Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells
por: Li, Jing, et al.
Publicado: (2019)

Suppression of CCT3 inhibits the proliferation and migration in breast cancer cells
por: Xu, Gang, et al.
Publicado: (2020)

Autophagy is induced and modulated by cholesterol depletion through transcription of autophagy-related genes and attenuation of flux
por: Shapira, Keren E., et al.
Publicado: (2021)

CDC42EP3 promotes colorectal cancer through regulating cell proliferation, cell apoptosis and cell migration
por: Feng, Qiang, et al.
Publicado: (2021)

EGCG induces human mesothelioma cell death by inducing reactive oxygen species and autophagy
por: Satoh, Motohiko, et al.
Publicado: (2013)

Autophagy contributes to apoptosis in A20 and EL4 lymphoma cells treated with fluvastatin
por: Qi, Xu-Feng, et al.
Publicado: (2013)

RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition
por: Rubio, María Fernanda, et al.
Publicado: (2017)

Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells
por: Saini, Heena, et al.
Publicado: (2021)

Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa
por: Shafi, Gowhar, et al.
Publicado: (2009)

Synergistic effects of isomorellin and forbesione with doxorubicin on apoptosis induction in human cholangiocarcinoma cell lines
por: Hahnvajanawong, Chariya, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8chsgalsp71p7bkflaqjptqe6t