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Depletion of membrane cholesterol compromised caspase-8 imparts in autophagy induction and inhibition of cell migration in cancer cells

BACKGROUND: Cholesterol in lipid raft plays crucial role on cancer cell survival during metastasis of cancer cells. Cancer cells are reported to enrich cholesterol in lipid raft which make them more susceptible to cell death after cholesterol depletion than normal cells. Methyl-β-cyclodextrin (MβCD)...

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Detalles Bibliográficos
Autores principales:	Kumar, Mukesh, Irungbam, Karuna, Kataria, Meena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819249/ https://www.ncbi.nlm.nih.gov/pubmed/29467593 http://dx.doi.org/10.1186/s12935-018-0520-4

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