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Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway

BACKGROUND: 5-Fluorouracil (5-FU) remains the most widely used agent to treat colorectal cancer (CRC). However, its clinical efficacy is currently limited by the development of drug resistance. Traditional Chinese Herbal Medicine (TCM) has been shown to enhance the efficacy of standard anticancer ag...

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Detalles Bibliográficos
Autores principales: Liu, Haizhou, Liu, Hui, Zhou, Zhiyi, Parise, Robert A., Chu, Edward, Schmitz, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819251/
https://www.ncbi.nlm.nih.gov/pubmed/29458395
http://dx.doi.org/10.1186/s12964-018-0218-1