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Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson’s disease-like motor dysfunction
Ghrelin exerts a wide range of physiological actions throughout the body and appears to be a promising target for disease therapy. Endogenous ghrelin receptors (GHSRs) are present in extrahypothalamic sites including the substantia nigra pars compacta (SNc), which is related to phenotypic dysregulat...
Autores principales: | Suda, Yukari, Kuzumaki, Naoko, Sone, Takefumi, Narita, Michiko, Tanaka, Kenichi, Hamada, Yusuke, Iwasawa, Chizuru, Shibasaki, Masahiro, Maekawa, Aya, Matsuo, Miri, Akamatsu, Wado, Hattori, Nobutaka, Okano, Hideyuki, Narita, Minoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819262/ https://www.ncbi.nlm.nih.gov/pubmed/29458391 http://dx.doi.org/10.1186/s13041-018-0349-8 |
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